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Tuesday, March 24, 2020

The man who may stop COVID-19



Lara Marlowe of the Irish Times had a terrific lead, "We could know within two weeks whether Professor Didier Raoult, the French virologist who heads the Mediterranean infectious and tropical disease institute in Marseille, will go down in history as the man who saved the world from COVID-19, or will be dismissed as an arrogant, misguided scientist who raised false hopes."

Doctor Raoult was the one who took hydroxycloroquine off the shelf, mixed it with azithromycin (another available drug) and used it to treat 24 French COVID-19 patients.

It worked. 18 of them tested negative after 6 days.

Marlowe wrote, "President Donald Trump apparently learned of Raoult’s experiment through a Twitter post by the billionaire entrepreneur Elon Musk. On March 20th, Trump wrongly claimed in a White House press briefing that the US Food and Drug Administration had approved what he called “the very powerful” drug chloroquine to treat Covid-19.

"Trump was corrected by Dr Anthony Fauci, a top expert on infectious disease and a pillar of the fight against corona virus. But Trump persisted, tweeting the following day that 'HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine.'"

The United States began testing this in New York, which is the nation's leader in COVID-19 patients.

He is a known figure in a relatively unknown medical community. The American Society for Microbiology interviewed him in 2018.

It said, "Dr. Didier Raoult considers himself a 'microbe fisher,' always 'fishing' to discover new microbes.  He says that in order to fish successfully, you need to first create the correct fishing pole (tools), and then fish in places where no one else is fishing.

"Dr. Raoult is the Director of the Mediterranean Infection Foundation at the Aix-Marseille University, France, and he has “caught” a number of unique microbes over the course of his career, including giant viruses. 

"He’s also 'caught'” a number of bacteria responsible for various diseases, including the causative agent of Whipple’s disease, and he even has two bacteria named after him. 

"Dr. Raoult talks about what is special about giant viruses, how he found the bacterium that causes Whipple’s disease, the challenges of trying to get uncultured bacteria like Rickettsia to grow in the lab, and how he would be sailing if he weren’t a microbiologist."

He may have caught the big one, Elizabeth.

Be cautious, but hopeful.

French health minister Olivier VĂ©ran said, "The history of viral disease is strewn with false good news, disappointments and reckless risks."

Medicine.Net cited Raoult's test and said, "This follows encouraging in vitro results obtained by a Chinese team led by Xueting Yao, from Peking University Third Hospital, Beijing, China, which were published online by the journal Clinical Infectious Diseases on March 9th. However, the data were deemed insufficient by the infection community to recommend the compound as a treatment.

"Moreover, chloroquine is not listed among the four treatments studied as part of the recently launched European clinical trial piloted by Inserm, which includes 3200 severe hospitalized patients, including 800 French patients.

"Chloroquine was ruled out due to the risk of interactions with other medications for common comorbidities in infected patients, and because of possible adverse effects in patients undergoing resuscitation."

Fair warning.

Now get on with the tests, and start saving lives. Maybe.

28 comments:

  1. I don't know about Chloroquine, but Azithromycin truly is a miracle drug. I have had several bouts with pneumonia, and when I do the VA gives me a Zithromax Z-Pak. I can feel a marked difference within a few hours, and within a day or two I am back to normal. - Elric

    ReplyDelete
    Replies
    1. There is a vaccine for pneumonia. One shot and you are good for life, or so my doctor told me.
      NB

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    2. It takes two shots I recently learned, and received my second a few months ago.

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    3. From what I understand, the vaccine is for bacterial pneumonia. Covid-19 is a viral pneumonia. I have had both shots also.

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    4. My husband is an 82 year old AF Vet who did take those shots but under unusual circumstances (swallowing food down the airway). The bacteria went into his lungs and he developed pneumonia and was hospitalized 10 days. Personally, I think the shots do work under normal circumstances.

      Kate

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    5. The "pneumonia shot" is a confusing example of oversimplification of language. The pair of vaccines collectively known as the pneumonia shot provide protection from diseases caused by one specific bacteria, namely the Streptococcus pneumoniae bacteria sometimes called Pneumococci. This pair of vaccines greatly reduces the likelihood of infection and death from infections caused by this bacteria, but they do not protect from pneumonia generally. For instance, it does not prevent viral pneumonias such as the viral pneumonia associated with influenza, or with coronavirus.

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  2. And we've all said, at one time or another, that President Trump should quit tweeting.

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    Replies
    1. Just to clarify, so far I have never thought Trump should stop tweeting. It's a truly effective way to control the narrative and bypass the enemedia. Greatest President in 100+ years!

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    2. When the mainstream media stop printing/broadcasting/tweeting/streaming etc, then Pres. Trump can decrease (but not stop) his tweets.

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    3. Prof. Raoult is a classic scientist.Testing the theory and see if it holds up no computer modeling-field work. That is where you get results.Trump's right in sending the meds to NYC. Note that Cuomo
      is not arguing...

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    4. Trump will quit tweeting when the media quit lying.

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    5. Trump only tweets:

      1) to punch back when he is lied about
      2) to punch through when his message is being distorted or blocked
      3) to distract, as part of a strategy

      I'm okay with all of that; and most of it is caused by the Left. Stop attacking or blocking him, and you'll find most of his tweets will stop.

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    6. I agree and have been explaining this to people before the 2016 election as to why President Trump has to tweet, right now with the MSM the way it is, this is the only way to get his messages to the public.
      Keep on tweeting Mr. President.

      Kate

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    7. I have known quite a few who had the P vaccines and still got pneumonia???

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  3. this story will old in 2 wks people will go back to work and wear mask, and be careful in their actions otherwis the economy we will have a depression people spends they do nt save..

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  4. if monsieur didier who is coucou they all are and arrogant who cares the french are always right....i am

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  5. Is Whipple's Disease the one that causes excessive purchasing of toilet paper?

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  6. With respect to chloroquine, I was issued a supply as an antimalarial prophylactic when I served in Vietnam 50 years ago. If it is effective here as so far indicated, Dr. Raoult will be honored as the Louis Pasteur of our century.
    NB

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  7. The FDA HAS is allowing not general use, but doctors decisions on whether or not to use it. Hundred of thousands of doses have been sent to NY by the FDA per news reports. So the President was not wrong just open to misinterpretation which has been clarified.

    ReplyDelete
    Replies
    1. They constantly misinterpret him. That’s ok. We know the game.

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  8. Doctors will find only one strong side effect: An immediate and persistent urge to vote for Donald John Trump.

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  9. A lot of misinformation out there. For example, Africa is malaria ridden so 'pundits' use the 'low incidence' of Wuhan there as proof that chloroquine (an anti-malarial drug) works. Problem is, nobody's testing much for the incidence of Wuhan in Africa and, anyway, chloroquine isn't used there because it doesn't work against the African strain of malaria.

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  10. BTW, the doc bears a little bit of resemblance to that famous Cher Slayer, Gregg Allman. Play Whipping Post, man!

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  11. Hats off to Dr. Raoult.
    Usually it is a lot of committees and bureaucrats who have to OK the medicine. Looks like he took the bull by the horns.
    Anything to get all these faceless bureaucrats out of our hair. They have stood in the way of a lot of drug discoveries and widespread use of medicines, and after trials and years of red tape, the medicines are so expensive that no one can afford them.

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  12. It's great news. I heard that the Professor would have announced it sooner, but some idiot started erasing his blackboard....

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    Replies
    1. Are claims that Dr Raoult is urging Africans to turn down the covid 19 being sent to Africa for trial, true?? The claim is making rounds on social media

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